⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900055 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL5232150 | 0.80 | — | — | |
| SCHEMBL15229171 | 0.79 | — | — | |
| SCHEMBL722127 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL10774518 | 0.78 | — | — | |
| SCHEMBL2912153 | 0.77 | ACHE (0.48) | — | |
| SCHEMBL2656053 | 0.77 | ACHE (0.48) | — | |
| SCHEMBL27972879 | 0.76 | ACHE (0.43) | — | |
| SCHEMBL24514589 | 0.76 | CHRNB2 (0.52) | — | |
| SCHEMBL851200 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347866-B | As the noval chemical compound of the respiratory stimulant for the treatment of control of breathing discomfort or disease | GALLEON PHARMACEUTICALS, INC. (US) | 2016-05-18 | — | — | CN | disclosed |
| CN-104602694-A | Novel compounds and compositions for treatment of breathing control disorders or diseases | GALLEON PHARMACEUTICALS INC | 2015-05-06 | — | — | CN | disclosed |
| CN-103347866-A | Novel compound as respiratory stimulants for treatment of breathing control disorder or disease | GALLEON PHARMACEUTICALS INC | 2013-10-09 | — | — | CN | disclosed |
| US-20080206182-A1 | Conjugates of a Polymer and a Protein Linked by an Oxime Group | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| US-20080206182-A1 | Conjugates of a Polymer and a Protein Linked by an Oxime Group | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-0925318-B1 | CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME | PPG IND OHIO INC (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-0925318-A1 | CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME | PPG INDUSTRIES, INC. (US) | 1999-06-30 | — | — | EP | disclosed |
| US-5759694-A | Carbamate functional polymers and oligomers and coating compositions containing same | PPG INDUSTRIES, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1998010006-A1 | CARBAMATE FUNCTIONAL POLYMERS AND COMPOSITIONS CONTAINING SAME | PPG INDUSTRIES, INC. (US) | 1998-03-12 | — | — | WO | disclosed |