Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 5/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7721606 | 0.76 | S100A4 (0.47) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL16745449 | 0.73 | S100A4 (0.77) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL31362908 | 0.71 | S100A4 (1.00) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL1612462 | 0.71 | S100A4 (1.00) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL6866105 | 0.68 | S100A4 (0.61) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL61036 | 0.66 | CLK4 (0.47) | MEN1KMT2ATDP1RAB9AKDM4E | |
| SCHEMBL9669361 | 0.66 | S100A4 (0.69) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL27628643 | 0.66 | LOXL2 (0.45) | MEN1KMT2ARAB9AKDM4ENPC1 | |
| SCHEMBL6866019 | 0.66 | CDC25B (0.58) | S100A4CDC25BMEN1KMT2ATHRB | |
| SCHEMBL1612515 | 0.66 | S100A4 (1.00) | S100A4CDC25BMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004003193-A1 | NOVEL PLA2 ENZYME, IT'S ANTIBODY, ENZYME INHIBITOR AND USE AND THE PREPARATION METHODS THEREOF | KIM DAE-KYONG (KR) | 2004-01-08 | — | — | WO | claimed |
| US-20040001834-A1 | Phospholipase A2 enzyme, antibodies and inhibitors thereto | KIM, DAE-KYONG (KR) | 2004-01-01 | — | — | US | claimed |
| WO-2004003193-A1 | NOVEL PLA2 ENZYME, IT'S ANTIBODY, ENZYME INHIBITOR AND USE AND THE PREPARATION METHODS THEREOF | KIM DAE-KYONG (KR) | 2004-01-08 | — | — | WO | disclosed |
| US-20040001834-A1 | Phospholipase A2 enzyme, antibodies and inhibitors thereto | KIM, DAE-KYONG (KR) | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040001834-A1 | Phospholipase A2 enzyme, antibodies and inhibitors thereto | PLA2G4A, PLAA, PLA2G12A | S100A4 1099/4885CDC25B 1908/4885MEN1 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.