SCHEMBL6661896

SCHEMBL6661896

O=C(O)C(Sc1ccc(O)cc1)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 18/20 0.46
PTGES O14684 12/20 0.46
PPARG P37231 10/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27607346 0.78 CYP1A2 (0.43)
SCHEMBL6785391 0.78 MAPT (0.49) PPARG
SCHEMBL28392771 0.76 ALDH1A1 (0.45) ALOX5PTGESPPARG
SCHEMBL6655717 0.76 ADAM17 (0.59) ALOX5PTGESPPARG
SCHEMBL21961160 0.74 ALOX5 (0.46) ALOX5PTGESPPARG
SCHEMBL21964369 0.73 ALOX5 (0.47) ALOX5PTGESPPARG
SCHEMBL3045758 0.71 ALDH1A1 (0.40) ALOX5PPARG
SCHEMBL28140482 0.70 ALDH1A1 (0.52)
SCHEMBL328867 0.70 ALDH1A1 (0.52)
SCHEMBL6051357 0.70 ALDH1A1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100489027-C Flame-retardant epoxy resin composition and phosphorus-containing compound CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2009-05-20 CN disclosed
CN-1580120-A Flame-retardant epoxy resin composition and phosphorus-containing compound CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2005-02-16 CN disclosed
CN-1580108-A Phosphorus-containing compound ARTIFICIAL RESIN FACTORY CO LT (CN) 2005-02-16 CN disclosed
EP-1147080-B1 ALKYNYL CONTAINING HYDROXAMIC ACID COMPOUNDS AS TACE INHIBITORS WYETH CORP (US) 2004-07-21 EP disclosed