Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664310 | 0.86 | ALDH1A1 (0.53) | NPSR1HPGDTP53ALDH1A1KDM4E | |
| SCHEMBL6665368 | 0.85 | NPSR1 (0.52) | NPSR1HPGDTP53ALDH1A1KDM4E | |
| SCHEMBL6669041 | 0.84 | ALDH1A1 (0.48) | NPSR1HPGDTP53ALDH1A1KDM4E | |
| SCHEMBL6665392 | 0.84 | ALDH1A1 (0.51) | NPSR1HPGDTP53ALDH1A1KDM4E | |
| SCHEMBL6681189 | 0.83 | ALDH1A1 (0.61) | NPSR1HPGDTP53ALDH1A1CYP2D6 | |
| SCHEMBL6664323 | 0.80 | ALDH1A1 (0.50) | NPSR1HPGDALDH1A1CYP3A4CHRM3 | |
| SCHEMBL6680489 | 0.79 | KMT2A (0.49) | NPSR1TP53KDM4EMAPTCHRM3 | |
| SCHEMBL6663170 | 0.78 | CHRM3 (0.67) | ALDH1A1CHRM3HDAC1HDAC2CHRM2 | |
| SCHEMBL6665574 | 0.74 | MEN1 (0.57) | ALDH1A1MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL6668837 | 0.73 | CHRM3 (0.49) | TP53ALDH1A1ALOX15L3MBTL1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |