Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680489 | 0.92 | KMT2A (0.49) | NPSR1KDM4EMAPTCHRM3TP53 | |
| SCHEMBL6665392 | 0.91 | ALDH1A1 (0.51) | ALDH1A1NPSR1KDM4EUSP2CYP1A2 | |
| SCHEMBL6665368 | 0.86 | NPSR1 (0.52) | ALDH1A1NPSR1KDM4EUSP2CYP1A2 | |
| SCHEMBL6664439 | 0.86 | CHRM3 (0.56) | L3MBTL1CHRM3TP53KMT2A | |
| SCHEMBL6681189 | 0.86 | ALDH1A1 (0.61) | ALDH1A1NPSR1CYP2D6CYP2C9CHRM3 | |
| SCHEMBL6664922 | 0.86 | NPSR1 (0.48) | ALDH1A1NPSR1KDM4EUSP2CYP1A2 | |
| SCHEMBL6669041 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4EUSP2CYP1A2 | |
| SCHEMBL6663170 | 0.83 | CHRM3 (0.67) | ALDH1A1CHRM3CHRM2CHRM1NPC1 | |
| SCHEMBL6664269 | 0.82 | NPC1 (0.64) | ALDH1A1NPSR1CYP1A2MAPTCYP2C9 | |
| SCHEMBL21052224 | 0.82 | CHRM3 (0.75) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |