Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663415 | 0.81 | ROCK2 (0.45) | MAOBMEN1KMT2AMAOADAO | |
| SCHEMBL6155072 | 0.80 | ALDH1A1 (0.51) | MAOBMEN1KMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL6153764 | 0.77 | MAOB (0.55) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6153761 | 0.76 | MAOB (0.56) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2272164 | 0.73 | APP (0.69) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3228582 | 0.71 | APP (0.82) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15818934 | 0.70 | MRGPRX4 (0.57) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15211218 | 0.70 | MAOB (0.50) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6154843 | 0.69 | MAOB (0.52) | MAOBAPPMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3894912 | 0.69 | MAOB (0.53) | MAOBKMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |