Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 4/20 | 0.40 |
| ▸ | APOB | P04114 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533119 | 0.90 | MTTP (0.48) | MTTPAPOBKDM4EALDH1A1KMT2A | |
| SCHEMBL14288688 | 0.81 | MTTP (0.52) | MTTPAPOBKDM4EALDH1A1KMT2A | |
| SCHEMBL8318404 | 0.80 | L3MBTL1 (0.42) | NAMPTALDH1A1KMT2A | |
| SCHEMBL533668 | 0.77 | HDAC7 (0.43) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL532826 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1POLBTSHR | |
| SCHEMBL6663843 | 0.76 | NOTUM (0.44) | MTTPAPOBTRPV4FABP4KDM4E | |
| SCHEMBL532809 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL6669985 | 0.76 | PARP10 (0.40) | MTTPAPOBFABP4NTRK1FABP5 | |
| SCHEMBL8320252 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1POLB | |
| SCHEMBL532962 | 0.74 | GAA (0.45) | KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |