Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661794 | 0.81 | CTSB (0.51) | CTSLCTSSCTSBPSMB5CTSK | |
| SCHEMBL6664026 | 0.79 | MAPT (0.48) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8343457 | 0.76 | CTSK (0.51) | TACR1CTSLCTSSCTSBPSMB5 | |
| SCHEMBL6683867 | 0.76 | CTSK (0.51) | TACR1CTSLCTSSCTSBPSMB5 | |
| SCHEMBL6666188 | 0.76 | CTSB (0.57) | CTSLCTSSCTSBPSMB5CTSK | |
| SCHEMBL6665963 | 0.73 | PSMB5 (0.41) | CTSLCTSSCTSBPSMB5CTSK | |
| SCHEMBL6662946 | 0.73 | PSMB5 (0.55) | CTSLCTSSCTSBPSMB5CTSK | |
| SCHEMBL6664032 | 0.72 | MEN1 (0.38) | TACR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15462622 | 0.71 | MME (0.50) | CTSLCTSSCTSBPSMB5CTSK | |
| SCHEMBL6661796 | 0.71 | CTSB (0.54) | CTSLCTSSCTSBPSMB5CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |