Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664022 | 0.72 | TACR1 (0.42) | MEN1KMT2AMAPTHDAC3HDAC4 | |
| SCHEMBL6664026 | 0.71 | MAPT (0.48) | MEN1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL5365857 | 0.62 | MAPT (0.80) | MEN1ALDH1A1KMT2AMAPTHDAC3 | |
| SCHEMBL5365861 | 0.62 | MAPT (0.80) | MEN1ALDH1A1KMT2AMAPTHDAC3 | |
| SCHEMBL10825085 | 0.62 | MEN1 (0.77) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL23451331 | 0.61 | MEN1 (0.62) | MEN1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL23451332 | 0.61 | MEN1 (0.62) | MEN1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL6661796 | 0.61 | CTSB (0.54) | MEN1ALDH1A1HPGDKMT2ACTSS | |
| SCHEMBL6683867 | 0.60 | CTSK (0.51) | MEN1KMT2ATACR1CTSSCTSK | |
| SCHEMBL8343457 | 0.60 | CTSK (0.51) | MEN1KMT2ATACR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | disclosed |