Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.51 |
| ▸ | CTSB | P07858 | 9/20 | 0.51 |
| ▸ | CTSS | P25774 | 7/20 | 0.51 |
| ▸ | CTSL | P07711 | 7/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343457 | 1.00 | CTSK (0.51) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL6662946 | 0.82 | PSMB5 (0.55) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL6665971 | 0.81 | PSMB5 (0.52) | CTSKCTSBPSMB5RENCASP1 | |
| SCHEMBL6666188 | 0.79 | CTSB (0.57) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL25465166 | 0.79 | PSMB5 (0.65) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL30500174 | 0.79 | PSMB5 (0.65) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL16024932 | 0.79 | PSMB5 (0.65) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL12826819 | 0.79 | PSMB5 (0.65) | CTSKCTSBCTSSCTSLPSMB5 | |
| SCHEMBL6664026 | 0.77 | MAPT (0.48) | CTSBCTSSCTSLPSMB5CASP1 | |
| SCHEMBL15462629 | 0.77 | CASP1 (0.56) | CTSKCTSBCTSSCTSLPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014882-A2 | PROTEASOME INHIBITORS : PEPTIDE DERIVATIVES HAVING C-TERMINAL HETEROARYL GROUPS | AXYS PHARMACEUTICALS (US) | 2004-02-19 | — | — | WO | claimed |