SCHEMBL666491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6781993	0.82	KDM4E (0.56)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL29951344	0.81	GAA (0.59)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL21649334	0.79	ALDH1A1 (0.37)	GAAKDM4EPOLBALDH1A1LMNA
	SCHEMBL6582728	0.79	KDM4E (0.67)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL31335674	0.78	GAA (0.54)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL28707342	0.78	GAA (0.64)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL24329339	0.77	GAA (0.50)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL166802	0.77	GAA (0.50)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL11385067	0.77	GAA (0.63)	GAAKDM4EPOLBHTTALDH1A1
	SCHEMBL1918973	0.77	GAA (0.50)	GAAKDM4EPOLBHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.