Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666751 | 0.91 | HSD17B10 (0.52) | TSHRHSD17B10CYP2A6CYP19A1KDM4E | |
| SCHEMBL6661170 | 0.90 | CYP2A6 (0.51) | TSHRHSD17B10CYP2A6CYP19A1ALDH1A1 | |
| SCHEMBL6661128 | 0.89 | KMT2A (0.36) | ACACBPSMB5ALDH1A1KIF11KCNH2 | |
| SCHEMBL6666034 | 0.85 | TSHR (0.34) | TSHRACACBPSMB5ALDH1A1L3MBTL1 | |
| SCHEMBL6660765 | 0.85 | MEN1 (0.42) | TSHRPSMB5ALDH1A1KCNH2 | |
| SCHEMBL6661144 | 0.84 | KMT2A (0.43) | ACACBPSMB5KDM4EALDH1A1GAA | |
| SCHEMBL6662750 | 0.83 | HTR2A (0.40) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6661968 | 0.83 | HTR2A (0.40) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6661249 | 0.82 | KDM4E (0.38) | KDM4EALDH1A1GAAHPGDL3MBTL1 | |
| SCHEMBL6666040 | 0.81 | ALDH1A1 (0.33) | KDM4EALDH1A1GAAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |