Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662033 | 0.89 | ALDH1A1 (0.42) | LMNAALDH1A1CASRL3MBTL1TSHR | |
| SCHEMBL6661144 | 0.88 | KMT2A (0.43) | LMNAALDH1A1CASRL3MBTL1GAA | |
| SCHEMBL6666034 | 0.87 | TSHR (0.34) | LMNAALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL6664947 | 0.85 | PDE2A (0.44) | ALDH1A1TSHR | |
| SCHEMBL6663070 | 0.85 | HTR2A (0.39) | LMNAALDH1A1CASRL3MBTL1GAA | |
| SCHEMBL6664134 | 0.84 | ALDH1A1 (0.35) | LMNAALDH1A1CASRL3MBTL1TSHR | |
| SCHEMBL6663001 | 0.84 | ALDH1A1 (0.33) | LMNAALDH1A1CASRL3MBTL1TSHR | |
| SCHEMBL6666975 | 0.83 | FAAH (0.43) | LMNAALDH1A1 | |
| SCHEMBL6661170 | 0.83 | CYP2A6 (0.51) | LMNAALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL6662930 | 0.83 | PPARG (0.35) | LMNAL3MBTL1GAAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |