Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667620 | 0.95 | PSMB5 (0.44) | PSMB5PSMB8PSEN1PSEN2APH1B | |
| SCHEMBL10972441 | 0.81 | LMNA (0.43) | PSMB5PSMB8CTSBLMNASMN1; SMN2 | |
| SCHEMBL6838403 | 0.81 | LMNA (0.47) | PSMB5PSMB8LMNASMN1; SMN2 | |
| SCHEMBL10653540 | 0.81 | LMNA (0.47) | PSMB5PSMB8LMNASMN1; SMN2 | |
| SCHEMBL6843141 | 0.77 | MC4R (0.43) | PSMB5PSMB8PSEN1PSEN2APH1B | |
| SCHEMBL6845514 | 0.77 | MC4R (0.43) | PSMB5PSMB8PSEN1PSEN2APH1B | |
| Ambamustine SCHEMBL62822 | 0.76 | LMNA (0.41) | PTPN1LMNASMN1; SMN2 | |
| Ambamustine SCHEMBL1419557 | 0.76 | LMNA (0.40) | PTPN1LMNASMN1; SMN2 | |
| SCHEMBL11129156 | 0.76 | HTT (0.39) | PSMB5PSMB8PTPN1LMNASMN1; SMN2 | |
| SCHEMBL11122837 | 0.75 | LMNA (0.42) | CTSBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024755-A2 | SARCOLYSYL DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF | LIPAL BIOCHEMICALS AG (CH) | 2004-03-25 | — | — | WO | disclosed |