Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667515 | 0.92 | ESR1 (0.53) | ALDH1A1LMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL3817682 | 0.89 | TSHR (0.52) | ALDH1A1LMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL9498545 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9499271 | 0.86 | NPSR1 (0.53) | ALDH1A1LMNANPSR1MAPTMEN1 | |
| SCHEMBL21396286 | 0.86 | PDCD1 (0.61) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL18464124 | 0.86 | PDCD1 (0.61) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL1129618 | 0.86 | ESR1 (0.64) | ALDH1A1LMNASMN1; SMN2NPSR1MAPT | |
| SCHEMBL9500077 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2NPSR1MAPT | |
| SCHEMBL9499131 | 0.85 | UTS2R (0.60) | ALDH1A1USP2HTTSLC6A9ESR1 | |
| SCHEMBL9500237 | 0.85 | NPC1 (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |