Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672200 | 0.82 | MTOR (0.46) | MTORRAB9ANPC1NAMPTEPHX1 | |
| SCHEMBL4350068 | 0.79 | MTOR (0.67) | MTORNAMPTEPHX2CNR1MCHR1 | |
| SCHEMBL6226495 | 0.78 | CHRNA7 (0.51) | MTORRAB9ANPC1NAMPTEPHX1 | |
| SCHEMBL4354215 | 0.76 | EPHX1 (0.61) | RAB9ANPC1NAMPTEPHX1EPHX2 | |
| SCHEMBL6672770 | 0.74 | MAPT (0.46) | CCR3MAPT | |
| SCHEMBL6229028 | 0.73 | MTOR (0.56) | MTORRAB9ANAMPTCNR1CCR3 | |
| SCHEMBL4348910 | 0.72 | EPHX2 (0.69) | MTORRAB9AEPHX2MAPT | |
| SCHEMBL6254974 | 0.71 | MEN1 (0.44) | MAPT | |
| SCHEMBL23747543 | 0.71 | RAB9A (0.78) | RAB9ANPC1NAMPTEPHX1POLB | |
| SCHEMBL4353993 | 0.71 | MTOR (0.67) | MTORRAB9ANAMPTCNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |