Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668636 | 0.82 | MTOR (0.48) | MTORNAMPTRAB9ANPC1EPHX1 | |
| SCHEMBL6226495 | 0.77 | CHRNA7 (0.51) | MTORNAMPTRAB9ANPC1EPHX1 | |
| SCHEMBL6699059 | 0.77 | EPHX2 (0.39) | EPHX1EPHX2 | |
| SCHEMBL6673094 | 0.75 | MTOR (0.43) | MTORNAMPTEPHX1EPHX2CCR3 | |
| SCHEMBL4355887 | 0.73 | MTOR (0.67) | MTORNAMPTTRPV1 | |
| SCHEMBL6225471 | 0.72 | SMN1; SMN2 (0.36) | MTORTRPV1LMNAL3MBTL1MAPT | |
| SCHEMBL4343621 | 0.71 | EPHX1 (0.56) | RAB9ANPC1EPHX1EPHX2POLB | |
| SCHEMBL6672789 | 0.70 | EPHX1 (0.60) | RAB9ANPC1EPHX1EPHX2TRPV1 | |
| SCHEMBL6229028 | 0.69 | MTOR (0.56) | MTORNAMPTRAB9ACNR1TRPV1 | |
| SCHEMBL4350115 | 0.69 | BAZ1A (0.65) | MTORRAB9AEPHX2TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |