Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667754 | 0.81 | AKR1C3 (0.39) | POLA1KCNH2NR1H4RAB9AENPP2 | |
| SCHEMBL6667470 | 0.79 | INSR (0.39) | POLA1KCNH2NR1H4RAB9AENPP2 | |
| SCHEMBL7472513 | 0.77 | AKR1C3 (0.36) | POLA1KCNH2NR1H4RAB9AENPP2 | |
| SCHEMBL6667774 | 0.76 | CHEK1 (0.46) | POLA1KCNH2NR1H4KDM4ERAB9A | |
| SCHEMBL7007040 | 0.76 | PDE1B (0.45) | POLA1KCNH2NR1H4RAB9AENPP2 | |
| SCHEMBL7478855 | 0.75 | POLA1 (0.39) | POLA1KCNH2NR1H4RAB9AENPP2 | |
| SCHEMBL6669289 | 0.74 | NPC1 (0.40) | POLA1KCNH2KDM4ERAB9AENPP2 | |
| SCHEMBL6670571 | 0.74 | KDM4E (0.39) | KCNH2KDM4EENPP2SMN1; SMN2 | |
| SCHEMBL7475511 | 0.74 | NR1H4 (0.38) | POLA1KCNH2NR1H4RAB9AAKR1C3 | |
| SCHEMBL6667531 | 0.72 | NR1H4 (0.34) | KCNH2NR1H4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |