Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970366 | 0.87 | MEN1 (0.46) | KMT2APOLBMEN1NPC1SMN1; SMN2 | |
| SCHEMBL23409168 | 0.85 | RAB9A (0.46) | LDHAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1970294 | 0.85 | MEN1 (0.44) | KMT2AGAAMEN1MAPTRAB9A | |
| SCHEMBL6366891 | 0.84 | SMN1; SMN2 (0.43) | KMT2APOLBMEN1NPC1MAPT | |
| SCHEMBL11770256 | 0.83 | ESR1 (0.49) | ALOX15KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL27971666 | 0.82 | MAPT (0.47) | KMT2AGAAPOLBEPHX2MEN1 | |
| SCHEMBL2554850 | 0.82 | MAPT (0.47) | KMT2AGAAMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3232287 | 0.82 | CA12 (0.45) | GAAPOLBEPHX2MAPTSMN1; SMN2 | |
| SCHEMBL5313250 | 0.82 | L3MBTL1 (0.51) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1516027 | 0.81 | MMP8 (0.53) | KMT2AGAAMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213279-B1 | VENLAFAXINE PRODUCTION PROCESS | MEDICHEM SA (ES) | 2004-09-15 | — | — | EP | disclosed |
| US-6645983-B1 | Heterocyclic imines such as 3-(4-methoxyphenyl)-1,4-dihydro-4 -quinolinone, used as anticarcinogenic agents having cytolysis efficiency; side effect reduction | LABORATOIRE L. LAFON (FR) | 2003-11-11 | — | — | US | disclosed |
| US-6506941-B1 | Venlafaxine production process | MEDICHEM, S.A. (ES) | 2003-01-14 | — | — | US | disclosed |
| EP-1213279-A1 | VENLAFAXINE PRODUCTION PROCESS | Medichem S.A. (ES) | 2002-06-12 | — | — | EP | disclosed |