Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770256 | 0.88 | ESR1 (0.49) | KMT2ASMN1; SMN2GAAMAPTALDH1A1 | |
| SCHEMBL27971666 | 0.86 | MAPT (0.47) | MEN1KMT2AGAAHTTMAPT | |
| SCHEMBL3232287 | 0.86 | CA12 (0.45) | SMN1; SMN2GAAHTTMAPTALDH1A1 | |
| SCHEMBL2554850 | 0.86 | MAPT (0.47) | MEN1KMT2ASMN1; SMN2GAAHTT | |
| SCHEMBL1516027 | 0.86 | MMP8 (0.53) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL6669586 | 0.85 | ALOX15 (0.47) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL1970366 | 0.85 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6971962 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6141592 | 0.83 | NAMPT (0.42) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL6367721 | 0.82 | KDM4E (0.36) | MEN1KMT2ASMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |