Salsalate

Salsalate

SCHEMBL668243

CCCC[P+](CCCC)(CCCC)CCCC.O=C(Oc1ccccc1C(=O)[O-])c1ccccc1O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52
LMNA P02545 4/20 0.52
KMT2A Q03164 5/20 0.45
MEN1 O00255 3/20 0.45
RECQL P46063 1/20 0.45
ALOX15 P16050 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
CYP3A4 P08684 2/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 2/20 0.41
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HTT P42858 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL666959 0.85 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10LMNA
Salsalate SCHEMBL11218871 0.85 KDM4E (0.52) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL23214372 0.85 LMNA (0.41) KDM4EALDH1A1HPGDHSD17B10LMNA
Aspirin SCHEMBL23214416 0.84 PTGS2 (0.50) KDM4EALDH1A1HPGDHSD17B10LMNA
Salsalate SCHEMBL668410 0.84 KDM4E (0.51) KDM4EALDH1A1HPGDHSD17B10LMNA
Salsalate SCHEMBL18889812 0.82 HSD17B10 (0.70) KDM4EALDH1A1HPGDHSD17B10LMNA
Salsalate SCHEMBL4090721 0.82 HSD17B10 (0.70) KDM4EALDH1A1HPGDHSD17B10LMNA
Salsalate SCHEMBL4385161 0.81 HSD17B10 (0.68) KDM4EALDH1A1HPGDHSD17B10LMNA
Salicylic Acid SCHEMBL668244 0.80 KDM4E (0.53) KDM4EALDH1A1HPGDHSD17B10LMNA
Cetylpyridinium SCHEMBL666197 0.79 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278134-B2 Dual functioning ionic liquids and salts thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-03-08 US disclosed
US-20120046244-A1 DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2012-02-23 US disclosed
WO-2010078300-A1 DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2010-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046244-A1 DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF SLC6A6, SLC10A2, CLK2 KDM4E 4730/4885ALDH1A1 3146/4885HPGD 1301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.