Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 3/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30223118 | 0.84 | KDM4C (0.47) | KDM4CPKMADORA2AADORA1GPR142 | |
| SCHEMBL4779863 | 0.78 | LMNA (0.44) | KDM4CPKMADORA2AADORA1GPR142 | |
| SCHEMBL2514575 | 0.78 | PKM (0.43) | KDM4CPKMGPR142KDM4EMAPK1 | |
| SCHEMBL7281500 | 0.77 | EPHX2 (0.52) | CTSK | |
| SCHEMBL4779862 | 0.76 | PKM (0.42) | KDM4CPKMGPR142KDM4EMAPK1 | |
| SCHEMBL17025004 | 0.75 | KDM4C (0.51) | KDM4CPKMADORA2AADORA1GPR142 | |
| Malonic Acid SCHEMBL6672041 | 0.74 | KDM4C (0.39) | KDM4CPKMADORA2AADORA1GPR142 | |
| SCHEMBL8077417 | 0.74 | HPGD (0.46) | KDM4CADORA2AADORA1GPR142KDM4E | |
| SCHEMBL6099838 | 0.74 | NPSR1 (0.52) | KDM4CPKMADORA2AADORA1GPR142 | |
| SCHEMBL9841065 | 0.74 | KDM4C (0.40) | KDM4CPKMADORA2AADORA1GPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554634-A | HYPOTENSIVE | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-10 | — | — | US | disclosed |