Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6672935 | 0.96 | LMNA (0.36) | NR3C1EGLN1LMNATHRBMAPT | |
| SCHEMBL6672937 | 0.88 | LMNA (0.35) | NR3C1LMNAMAPTCNR2 | |
| SCHEMBL6667062 | 0.81 | POLB (0.37) | NR3C1LMNAMAPTCNR2 | |
| SCHEMBL6666974 | 0.80 | LMNA (0.39) | NR3C1EGLN1LMNATHRBMAPT | |
| SCHEMBL6198178 | 0.79 | EGLN1 (0.38) | NR3C1EGLN1LMNATHRBCNR2 | |
| SCHEMBL6201997 | 0.79 | EGLN1 (0.37) | NR3C1EGLN1LMNATHRBCNR2 | |
| SCHEMBL6197986 | 0.77 | EGLN1 (0.49) | NR3C1EGLN1LMNACNR2GSK3B | |
| SCHEMBL6199942 | 0.75 | NR3C1 (0.39) | NR3C1EGLN1LMNATHRBCNR2 | |
| Trifluoroacetic Acid SCHEMBL6198172 | 0.75 | LMNA (0.36) | EGLN1LMNAMAPTCNR2 | |
| SCHEMBL6198141 | 0.75 | EGLN1 (0.47) | NR3C1EGLN1LMNAMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |