Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672316 | 0.96 | NR3C1 (0.37) | LMNANR3C1CNR2MAPTEGLN1 | |
| SCHEMBL6672937 | 0.88 | LMNA (0.35) | LMNANR3C1CNR2POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL6198172 | 0.80 | LMNA (0.36) | LMNASLC2A1CNR2POLBMAPT | |
| SCHEMBL6667062 | 0.79 | POLB (0.37) | LMNANR3C1CNR2POLBMAPT | |
| SCHEMBL6666974 | 0.78 | LMNA (0.39) | LMNANR3C1CNR2POLBMAPT | |
| SCHEMBL6198178 | 0.76 | EGLN1 (0.38) | LMNANR3C1CNR2EGLN1THRB | |
| SCHEMBL6199942 | 0.75 | NR3C1 (0.39) | LMNANR3C1CNR2EPHX2EGLN1 | |
| SCHEMBL6201997 | 0.75 | EGLN1 (0.37) | LMNANR3C1CNR2EPHX2EGLN1 | |
| SCHEMBL6197986 | 0.73 | EGLN1 (0.49) | LMNANR3C1CNR2EGLN1 | |
| SCHEMBL6671910 | 0.72 | P2RX3 (0.36) | LMNANR3C1CNR2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |