Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6672935 | 0.88 | LMNA (0.36) | LMNANR3C1CNR2MAPTPOLB | |
| SCHEMBL6672316 | 0.88 | NR3C1 (0.37) | LMNANR3C1CNR2MAPT | |
| SCHEMBL6198179 | 0.81 | LMNA (0.35) | LMNANR3C1CNR2MAPTPOLB | |
| SCHEMBL6667062 | 0.71 | POLB (0.37) | LMNANR3C1CNR2MAPTPOLB | |
| SCHEMBL6666974 | 0.70 | LMNA (0.39) | LMNANR3C1CNR2MAPTPOLB | |
| Trifluoroacetic Acid SCHEMBL6198172 | 0.69 | LMNA (0.36) | LMNACNR2MAPTPOLBEPHX2 | |
| SCHEMBL6198178 | 0.68 | EGLN1 (0.38) | LMNANR3C1CNR2 | |
| SCHEMBL6201997 | 0.67 | EGLN1 (0.37) | LMNANR3C1CNR2EPHX2CYP1A2 | |
| SCHEMBL6199942 | 0.66 | NR3C1 (0.39) | LMNANR3C1CNR2EPHX2CYP1A2 | |
| SCHEMBL8122619 | 0.65 | NR3C1 (0.43) | LMNANR3C1CNR2MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |