Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3041159 | 0.93 | TIPARP (0.39) | TIPARPGRM1HDAC6AOC3IDH1 | |
| SCHEMBL3036235 | 0.81 | MAOA (0.49) | TIPARPMAOBMAOALMNAPTGS1 | |
| SCHEMBL6674186 | 0.81 | MAOA (0.49) | TIPARPMAOBMAOALMNAPTGS1 | |
| SCHEMBL5765558 | 0.76 | MAOB (0.42) | TIPARPGRM1MAOBMAOALMNA | |
| SCHEMBL3041156 | 0.75 | MAOB (0.43) | TIPARPGRM1MAOBMAOALMNA | |
| SCHEMBL3038203 | 0.75 | MAOB (0.43) | TIPARPGRM1MAOBMAOALMNA | |
| SCHEMBL6636437 | 0.75 | CALML3 (0.56) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6638114 | 0.74 | MAOA (0.65) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL3045062 | 0.70 | ALDH1A1 (0.47) | TIPARPGRM1HDAC6AOC3LMNA | |
| SCHEMBL5792891 | 0.68 | CYP11B2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |