Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68909 | 0.97 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| Fluoride SCHEMBL28120859 | 0.94 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR | |
| Arsenic SCHEMBL28094094 | 0.94 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL6519029 | 0.89 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL10318044 | 0.81 | CYP1A2 (0.46) | ESR1ESR2MAPTALDH1A1TDP1 | |
| SCHEMBL705667 | 0.81 | ALDH1A1 (0.36) | ESR1ESR2ALDH1A1 | |
| SCHEMBL197544 | 0.79 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL144807 | 0.79 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL9383203 | 0.79 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL23898214 | 0.77 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266903-B1 | Method of preparing an organosilicon compound | DOW CORNING ASIA LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-1266903-A1 | Method of preparing an organosilicon compound | DOW CORNING ASIA, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6326506-B1 | HYDROSILATION | DOW CORNING ASIA, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |