Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | S100A9 | P06702 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824709 | 0.91 | UTS2R (0.36) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6674024 | 0.89 | LMNA (0.39) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6680164 | 0.87 | PTPN11 (0.34) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6672793 | 0.86 | ALDH1A1 (0.43) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6674003 | 0.85 | S100A9 (0.37) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6679728 | 0.80 | S100A9 (0.37) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6818539 | 0.80 | UTS2R (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6824643 | 0.80 | UTS2R (0.35) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6678442 | 0.79 | S100A9 (0.37) | HTR6LMNAMEN1KMT2AMAPT | |
| SCHEMBL6678341 | 0.79 | HPGD (0.41) | HTR6PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |