Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S100A9 | P06702 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675715 | 0.93 | LMNA (0.39) | HPGDS100A9CYP17A1LMNAMAPT | |
| SCHEMBL6679728 | 0.93 | S100A9 (0.37) | HPGDS100A9LMNAMAPTHTT | |
| SCHEMBL6674003 | 0.91 | S100A9 (0.37) | S100A9CYP17A1LMNAMAPTHTT | |
| SCHEMBL6676986 | 0.90 | S100A9 (0.36) | HPGDS100A9CYP17A1LMNAMAPT | |
| SCHEMBL6825132 | 0.89 | FFAR4 (0.41) | HPGDS100A9CYP17A1LMNAMAPT | |
| SCHEMBL6678442 | 0.87 | S100A9 (0.37) | HPGDS100A9LMNAMAPTHTT | |
| SCHEMBL6822583 | 0.86 | PLA2G7 (0.38) | S100A9LMNAMAPTHTTPOLB | |
| SCHEMBL6672793 | 0.86 | ALDH1A1 (0.43) | S100A9LMNAMAPTHTTPOLB | |
| SCHEMBL6824849 | 0.83 | LMNA (0.39) | S100A9LMNAMAPTHTTPOLB | |
| SCHEMBL6822523 | 0.83 | UTS2R (0.41) | S100A9LMNAMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |