Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 3/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679728 | 0.88 | S100A9 (0.37) | S100A9SLC22A12HTTCCR2MEN1 | |
| SCHEMBL6674003 | 0.88 | S100A9 (0.37) | S100A9HTTCCR2MEN1KMT2A | |
| SCHEMBL6678341 | 0.87 | HPGD (0.41) | S100A9HTTMEN1KMT2ALMNA | |
| SCHEMBL6676986 | 0.87 | S100A9 (0.36) | S100A9SLC22A12HTTMEN1KMT2A | |
| SCHEMBL6672793 | 0.86 | ALDH1A1 (0.43) | S100A9HTTMEN1KMT2ALMNA | |
| SCHEMBL6680164 | 0.85 | PTPN11 (0.34) | S100A9PTPN11HTTMEN1KMT2A | |
| SCHEMBL6675715 | 0.85 | LMNA (0.39) | S100A9SLC22A12HTTMEN1KMT2A | |
| SCHEMBL6822583 | 0.81 | PLA2G7 (0.38) | S100A9HTTMEN1KMT2ALMNA | |
| SCHEMBL6825082 | 0.79 | SCN9A (0.35) | S100A9HTTMEN1KMT2ALMNA | |
| SCHEMBL6674472 | 0.79 | HTR6 (0.34) | S100A9HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |