SCHEMBL6674630

SCHEMBL6674630

CCN(CCCN)C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 2/20 0.45
HDAC6 Q9UBN7 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA9 Q16790 1/20 0.35
NAMPT P43490 1/20 0.33
CA7 P43166 1/20 0.33
CYP1A2 P05177 2/20 0.32
LMNA P02545 1/20 0.32
CTSK P43235 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SSTR4 P31391 1/20 0.32
HDAC3 O15379 1/20 0.31
NCOR2 Q9Y618 1/20 0.31
ACHE P22303 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20730041 0.97 CA14 (0.47) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL13784777 0.95 CA14 (0.48) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL5460363 0.91 CA14 (0.53) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL1028104 0.89 CA14 (0.41) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL1274075 0.89 CA14 (0.55) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL31324971 0.89 CA14 (0.51) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL17471898 0.88 CA14 (0.48) CA14HDAC6HDAC1HDAC2CA12
Hydrochloric Acid SCHEMBL3451895 0.87 CA14 (0.40) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL10226292 0.87 CA14 (0.54) CA14HDAC6HDAC1HDAC2CA12
SCHEMBL10226299 0.87 CA14 (0.54) CA14HDAC6HDAC1HDAC2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 EP disclosed
CN-116635028-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2023-08-22 CN disclosed
US-20220411396-A1 TRIOXOLANE AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-12-29 US disclosed
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 US disclosed
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 US disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 WO disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 WO disclosed
US-11318132-B2 Diversion-resistant opioid formulations ELYSIUM THERAPEUTICS, INC. (US) 2022-05-03 US disclosed
EP-3305784-B1 HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS JANSSEN PHARMACEUTICA NV (BE) 2020-08-12 EP disclosed
US-20200113893-A1 DIVERSION-RESISTANT OPIOID FORMULATIONS ELYSIUM THERAPEUTICS, INC. 2020-04-16 US disclosed
US-10314839-B2 Diversion-resistant opioid formulations ELYSIUM THERAPEUTICS, INC. (US) 2019-06-11 US disclosed
EP-2887952-B1 ANTIBODIES TO OLANZAPINE HAPTENS AND USE THEREOF JANSSEN PHARMACEUTICA NV (BE) 2019-05-15 EP disclosed
US-20160136153-A1 DIVERSION-RESISTANT OPIOID FORMULATIONS ELYSIUM THERAPEUTICS, INC. 2016-05-19 US disclosed
US-20090318424-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2009-12-24 US disclosed
US-20090318424-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2009-12-24 US disclosed
WO-2007147109-A2 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2007-12-21 WO disclosed
EP-1468688-A2 Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments Auckland Uniservices Limited (NZ) 2004-10-20 EP disclosed
US-20040192686-A1 Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments AUCKLAND UNISERVICES LIMITED (NZ) 2004-09-30 US disclosed
US-6063791-A N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use FOURNIER INDUSTRIE ET SANTE (FR) 2000-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CA14 4579/4885HDAC6 1919/4885HDAC1 2726/4885
US-20220411396-A1 TRIOXOLANE AGENTS ABCB4, SLC10A1, SLC10A2 CA14 1532/4885HDAC6 3841/4885HDAC1 3955/4885
US-20160136153-A1 DIVERSION-RESISTANT OPIOID FORMULATIONS OPRL1, OPRK1, OPRM1 CA14 3595/4885HDAC6 342/4885HDAC1 1116/4885
US-11318132-B2 Diversion-resistant opioid formulations OPRL1, OPRK1, OPRM1 CA14 3595/4885HDAC6 342/4885HDAC1 1116/4885
US-20200113893-A1 DIVERSION-RESISTANT OPIOID FORMULATIONS OPRL1, OPRK1, OPRM1 CA14 3595/4885HDAC6 342/4885HDAC1 1116/4885
US-20040192686-A1 Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments NPM1, DUOX1, NOX5 CA14 1811/4885HDAC6 649/4885HDAC1 389/4885
US-10314839-B2 Diversion-resistant opioid formulations OPRL1, OPRK1, OPRM1 CA14 3595/4885HDAC6 342/4885HDAC1 1116/4885
US-20090318424-A1 NOVEL COMPOUNDS MAPKAPK2, MAPKAPK3, CDC42BPB CA14 4675/4885HDAC6 635/4885HDAC1 658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.