Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6674631

CC(C)(C)c1ccc([S+](c2ccccc2)(c2ccccc2)(c2ccccc2)c2ccc(C(C)(C)C)cc2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HSD11B1 P28845 8/20 0.41
GPR3 P46089 2/20 0.41
HSD17B3 P37058 1/20 0.41
UQCRB P14927 1/20 0.41
HSD17B2 P37059 1/20 0.41
NPC1 O15118 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
PTPN1 P18031 1/20 0.37
KDM4E B2RXH2 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MAOA P21397 1/20 0.37
RORA P35398 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL29834793 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL51512 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL1270048 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL3136704 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL1002309 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL8640775 0.79 HSD11B1 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Tert-Butylbenzene SCHEMBL2964334 0.77 GPR3 (0.41) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Biphenyl SCHEMBL1360704 0.75 PTPN1 (0.43) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL29834722 0.74 TSHR (0.43) ALDH1A1HSD11B1GPR3HSD17B3UQCRB
Trifluoromethanesulfonic Acid SCHEMBL36543 0.74 ALDH1A1 (0.46) ALDH1A1HSD11B1GPR3HSD17B3UQCRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901043-B1 Radiation-sensitive resin composition JSR CORP (JP) 2004-10-27 EP disclosed
US-6120972-A COPOLYMER OF ACRYLIC ESTER AND CARBONATE WITH PHOTOACID GENERATOR FOR PHOTOSENSITIVE ELEMENTS JSR CORPORATION (JP) 2000-09-19 US disclosed
EP-0901043-A1 Radiation-sensitive resin composition JSR Corporation (JP) 1999-03-10 EP disclosed