Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6681157 | 0.99 | SIGMAR1 (0.40) | SIGMAR1P2RX1ALDH1A1TMPRSS4GPR35 | |
| SCHEMBL6684630 | 0.83 | GPR35 (0.37) | SIGMAR1P2RX1ALDH1A1TMPRSS4GPR35 | |
| SCHEMBL7243748 | 0.79 | CETP (0.36) | SIGMAR1P2RX1ALDH1A1TMPRSS4RAF1 | |
| SCHEMBL6674825 | 0.77 | P2RX1 (0.39) | P2RX1TMPRSS4GPR35RAF1BRAF | |
| SCHEMBL11881940 | 0.76 | KIF11 (0.51) | SIGMAR1MAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6681155 | 0.76 | P2RX1 (0.38) | P2RX1TMPRSS4GPR35RAF1BRAF | |
| SCHEMBL6674885 | 0.76 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1 | |
| SCHEMBL6676200 | 0.75 | LOXL2 (0.44) | SIGMAR1CA12CA1CA2CA9 | |
| SCHEMBL6680178 | 0.68 | SIGMAR1 (0.50) | SIGMAR1ALDH1A1 | |
| SCHEMBL27118826 | 0.68 | RXFP1 (0.46) | ALDH1A1GPR35RAF1BRAFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |