Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | GMNN | O75496 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465833 | 0.93 | FFAR1 (0.39) | MMP2GMNNLMNAMAPTNPSR1 | |
| SCHEMBL6860166 | 0.88 | GPR84 (0.50) | GPR84HSP90AA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL4464049 | 0.81 | PPARG (0.46) | GPR84MMP2GMNNLMNAMAPT | |
| SCHEMBL7785237 | 0.81 | PSMD14 (0.37) | HSP90AA1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL28341613 | 0.75 | PSMD14 (0.48) | GPR84HSP90AA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL26924194 | 0.75 | RECQL (0.43) | HSP90AA1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL10276873 | 0.75 | RECQL (0.43) | GPR84HSP90AA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL12095543 | 0.74 | CES2 (0.37) | MAPK1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9074998 | 0.74 | PSMD14 (0.73) | GPR84HSP90AA1PSMD14PLA2G1BMMP2 | |
| SCHEMBL10588884 | 0.73 | PSMD14 (0.40) | GPR84HSP90AA1PSMD14PLA2G1BMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040258649-A1 | Aqueous formulations comprising combinations of anionic and cationic surfactants for generating a yeild point | GOLDSCHMIDT AG (DE) | 2004-12-23 | — | — | US | disclosed |
| EP-1466959-A1 | Aqueous compositions containing anionic and cationic surfactants for obtaining a yield point | Goldschmidt AG (DE) | 2004-10-13 | — | — | EP | disclosed |