Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F3 | P13726 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675439 | 0.93 | GPR84 (0.40) | FFAR1FFAR4MAPTBLMLMNA | |
| SCHEMBL4464049 | 0.90 | PPARG (0.46) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL7785237 | 0.89 | PSMD14 (0.37) | MMP2FAAHSLC6A5FABP3 | |
| SCHEMBL6860166 | 0.82 | GPR84 (0.50) | FFAR1FFAR4PPARDMAPTBLM | |
| SCHEMBL22371941 | 0.78 | MMP2 (0.42) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL7768310 | 0.76 | ENPP2 (0.40) | MMP2FAAHFABP3 | |
| SCHEMBL6673254 | 0.76 | ENPP2 (0.40) | MMP2FAAHFABP3 | |
| SCHEMBL6740155 | 0.76 | SLC6A5 (0.51) | MAPTFAAHSLC6A5ALDH1A1HPGD | |
| SCHEMBL28391418 | 0.76 | PPARG (0.49) | FFAR1FFAR4PPARGPPARDPPARA | |
| SCHEMBL1027031 | 0.75 | LPAR3 (0.46) | BLMTDP1FAAHKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015036342-A1 | METHOD FOR PRODUCING ALKANE CABOXYLIC ACIDS | EVONIK INDUSTRIES AG (DE) | 2015-03-19 | — | — | WO | claimed |
| EP-3066065-B1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID AMIDES, DI-, TRI- OR POLYPEPTIDES OR PEPTIDE AMIDES | EVONIK DEGUSSA GMBH (DE) | 2019-06-19 | — | — | EP | disclosed |
| US-9878975-B2 | Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| EP-2917398-B1 | COMPOSITION FOR PERMANENTLY HYDROPHILIZING POLYOLEFIN FIBERS AND USE THEREOF | SCHILL + SEILACHER GMBH (DE) | 2016-12-07 | — | — | EP | disclosed |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | EVONIK DEGUSSA GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| EP-3066065-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | Evonik Degussa GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-20150292144-A1 | COMPOSITION FOR PERMANENTLY HYDROPHILIZING POLYOLEFIN FIBERS AND USE THEREOF | SCHILL + SEILACHER GMBH (DE) | 2015-10-15 | — | — | US | disclosed |
| WO-2015067450-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2868643-A1 | Catalytic hydrogenation for the preparation of amines from carboxylic acid amides, carboxylic acid amides, di-, tri- or polypeptides or peptide amides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
| WO-2015036342-A1 | METHOD FOR PRODUCING ALKANE CABOXYLIC ACIDS | EVONIK INDUSTRIES AG (DE) | 2015-03-19 | — | — | WO | disclosed |
| US-7597881-B2 | Use of ester quats in compositions as sand-repellent substances | GOLDSCHMIDT GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7297675-B2 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| EP-1844753-A2 | Utilisation of ester quats in compositions as sand repellent substances | Goldschmidt GmbH (DE) | 2007-10-17 | — | — | EP | disclosed |
| US-20070231289-A1 | Use of ester quats in compositions as sand-repellent substances | GOLDSCHMIDT GMBH (DE) | 2007-10-04 | — | — | US | disclosed |
| EP-1659109-B1 | Process for the preparation of highly concentrated, flowable aqueous betaine solutions | GOLDSCHMIDT GMBH (DE) | 2007-03-21 | — | — | EP | disclosed |
| US-20070015681-A1 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-01-18 | — | — | US | disclosed |
| US-7163916-B2 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2007-01-16 | — | — | US | disclosed |
| US-20060128599-A1 | Process for the preparation of highly concentrated flowable aqueous solutions of betaines | GOLDSCHMIDT GMBH (DE) | 2006-06-15 | — | — | US | disclosed |
| EP-1466959-A1 | Aqueous compositions containing anionic and cationic surfactants for obtaining a yield point | Goldschmidt AG (DE) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070231289-A1 | Use of ester quats in compositions as sand-repellent substances | CUTA, DLAT, CRAT | CHRM1 580/4885FFAR1 333/4885FFAR4 666/4885 |
| US-20160272571-A1 | Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides | DAO, DDC, HDGF | CHRM1 3589/4885FFAR1 3111/4885FFAR4 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.