Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 5/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465833 | 0.89 | FFAR1 (0.39) | MMP2FABP3SLC6A5FAAH | |
| SCHEMBL6675439 | 0.81 | GPR84 (0.40) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL7768310 | 0.80 | ENPP2 (0.40) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL6673254 | 0.80 | ENPP2 (0.40) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL22371941 | 0.77 | MMP2 (0.42) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6740155 | 0.77 | SLC6A5 (0.51) | CNR1SLC6A5FAAHCNR2 | |
| SCHEMBL1027031 | 0.77 | LPAR3 (0.46) | CNR1FAAHCNR2TRPV1 | |
| SCHEMBL7184129 | 0.76 | RECQL (0.39) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL29165752 | 0.76 | RECQL (0.39) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL4464049 | 0.76 | PPARG (0.46) | MMP2FABP3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801672-B1 | CLEAR, CONCENTRATED LIQUID FABRIC SOFTENER COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2001-10-04 | — | — | EP | claimed |