Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678687 | 0.82 | KDM4E (0.38) | KDM4EHIF1AGAAALDH1A1RAB9A | |
| SCHEMBL6681092 | 0.79 | ALDH1A1 (0.42) | KDM4EHIF1AGAAALDH1A1MAPT | |
| SCHEMBL6679997 | 0.79 | KDM4E (0.39) | KDM4EGAAALDH1A1RAB9AKMT2A | |
| SCHEMBL8771555 | 0.78 | IDO1 (0.39) | KDM4EGAARAB9ANPC1MAPT | |
| SCHEMBL6674836 | 0.77 | KDM4E (0.34) | KDM4EALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL6681940 | 0.77 | PKM (0.35) | KDM4EHIF1AGAAALDH1A1MAPT | |
| SCHEMBL6679126 | 0.74 | KDM4E (0.41) | KDM4EGAAALDH1A1RAB9AAAK1 | |
| SCHEMBL6680549 | 0.74 | HDAC8 (0.40) | KDM4EGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL6675896 | 0.74 | ALDH1A1 (0.41) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL6676958 | 0.73 | KDM4E (0.36) | KDM4ERAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |