Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678687 | 0.88 | KDM4E (0.38) | KDM4ENPC1MAPTRAB9AKDM4A | |
| SCHEMBL6674836 | 0.87 | KDM4E (0.34) | KDM4ENPC1MAPTRAB9AKDM4A | |
| SCHEMBL6680479 | 0.82 | CYP2C9 (0.39) | HDAC1 | |
| SCHEMBL6687614 | 0.79 | IDO1 (0.41) | KDM4ENPC1MAPTRAB9ACA1 | |
| SCHEMBL6681075 | 0.79 | NQO2 (0.39) | KDM4ENPC1MAPTRAB9ACA1 | |
| SCHEMBL8771555 | 0.79 | IDO1 (0.39) | KDM4ENPC1MAPTRAB9ACA1 | |
| SCHEMBL6676118 | 0.78 | CA2 (0.47) | KDM4ENPC1MAPTRAB9ACA1 | |
| SCHEMBL6675986 | 0.77 | GRM2 (0.32) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL6675872 | 0.76 | KCNA5 (0.35) | KDM4ENPC1MAPTRAB9AKDM4A | |
| SCHEMBL6679944 | 0.76 | GRM2 (0.32) | KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |