Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687614 | 0.88 | IDO1 (0.41) | IDO1NQO2KDM4ENPC1RAB9A | |
| SCHEMBL6681075 | 0.88 | NQO2 (0.39) | IDO1NQO2KDM4ENPC1RAB9A | |
| SCHEMBL6678687 | 0.85 | KDM4E (0.38) | CNR1CNR2KDM4ENPC1RAB9A | |
| SCHEMBL6676118 | 0.83 | CA2 (0.47) | KDM4ENPC1RAB9AMAPTCA1 | |
| SCHEMBL6675306 | 0.83 | NQO2 (0.38) | NQO2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6682001 | 0.81 | CA1 (0.41) | MAPTCA1CA2 | |
| SCHEMBL7244827 | 0.79 | NQO2 (0.43) | IDO1NQO2CNR1DRD2GAA | |
| SCHEMBL6676958 | 0.79 | KDM4E (0.36) | NQO2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6681092 | 0.78 | ALDH1A1 (0.42) | KDM4EQPCTMAPTGAA | |
| SCHEMBL6675899 | 0.78 | KDM4E (0.37) | KDM4ENPC1RAB9AQPCTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |