Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675005 | 0.86 | KMT2A (0.41) | CA2KMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6676190 | 0.85 | KMT2A (0.40) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6676381 | 0.82 | ALDH1A1 (0.39) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6676396 | 0.82 | KMT2A (0.40) | CA2KMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6676136 | 0.81 | ALDH1A1 (0.38) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6549806 | 0.79 | ALDH1A1 (0.42) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6676268 | 0.78 | CA1 (0.39) | CA2ALDH1A1 | |
| SCHEMBL6674882 | 0.78 | CFD (0.43) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6548531 | 0.78 | ALDH1A1 (0.41) | CA2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7242543 | 0.74 | HDAC4 (0.39) | KMT2AMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |