Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675005 | 0.85 | KMT2A (0.41) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6676190 | 0.84 | KMT2A (0.40) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6676175 | 0.82 | CA2 (0.40) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7242543 | 0.81 | HDAC4 (0.39) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6676381 | 0.80 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6676136 | 0.79 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6549806 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6548531 | 0.77 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6676180 | 0.75 | SIGMAR1 (0.47) | KMT2AMEN1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10385139 | 0.75 | KMT2A (0.53) | KMT2AMEN1ALDH1A1TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |