Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6674891 | 0.98 | TAAR1 (0.40) | TAAR1MAPTGAAALDH1A1GRIN2D | |
| SCHEMBL6680198 | 0.87 | ALDH1A1 (0.43) | TAAR1MAPTGAAALDH1A1 | |
| SCHEMBL17976239 | 0.81 | POLB (0.54) | MAPTGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6676239 | 0.77 | ADRA1A (0.49) | TAAR1MAPTALDH1A1HTR2A | |
| SCHEMBL6676422 | 0.77 | ALDH1A1 (0.42) | MAPTGAAALDH1A1POLB | |
| SCHEMBL6676347 | 0.77 | ALDH1A1 (0.39) | MAPTGAAALDH1A1GRIN2DGRIN3B | |
| SCHEMBL6675316 | 0.77 | PNMT (0.41) | MAPTGAAALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6679352 | 0.76 | ADRA1A (0.48) | TAAR1MAPTALDH1A1HTR2A | |
| Hydrochloric Acid SCHEMBL6674248 | 0.76 | PNMT (0.40) | MAPTGAAALDH1A1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6675363 | 0.76 | ALDH1A1 (0.41) | MAPTGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |