Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139613 | 0.84 | CYP1A2 (0.39) | CYP1A2CYP2A6HTR1DTSHRACHE | |
| SCHEMBL9771639 | 0.75 | NR4A2 (0.45) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL9771602 | 0.72 | KMT2A (0.35) | ACHEALDH1A1LMNARAB9AMEN1 | |
| SCHEMBL4957320 | 0.72 | MAPT (0.50) | TSHRACHEALDH1A1POLBL3MBTL1 | |
| SCHEMBL8945494 | 0.72 | ADRA2A (0.39) | CYP1A2CYP2A6TSHRPOLBLMNA | |
| SCHEMBL7691868 | 0.72 | POLB (0.38) | HTR1DTSHRACHEALDH1A1POLB | |
| SCHEMBL2927525 | 0.71 | ALDH1A1 (0.54) | CYP1A2CYP2A6HTR1DTSHRACHE | |
| SCHEMBL770140 | 0.71 | CYP1A2 (0.47) | CYP1A2CYP2A6HTR1DTSHRACHE | |
| SCHEMBL6354922 | 0.70 | POLB (0.37) | HTR1DTSHRACHEALDH1A1POLB | |
| SCHEMBL1006539 | 0.69 | CYP1A2 (0.45) | CYP1A2CYP2A6HTR1DTSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | PETROCHINA COMPANY LIMITED (CN) | 2020-11-26 | — | — | US | claimed |
| CN-111978346-A | Arylamine silane compound, propylene polymerization catalyst, preparation and application thereof | 中国石油天然气股份有限公司 | 2020-11-24 | — | — | CN | claimed |
| US-11535638-B2 | Arylaminosilane compound, propylene polymerization catalyst and preparation thereof | PETROCHINA COMPANY LIMITED (CN) | 2022-12-27 | — | — | US | disclosed |
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | PETROCHINA COMPANY LIMITED (CN) | 2020-11-26 | — | — | US | disclosed |
| CN-111978346-A | Arylamine silane compound, propylene polymerization catalyst, preparation and application thereof | 中国石油天然气股份有限公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-1238996-B1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | ZEON CORP (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6653424-B1 | Using polymerization catalyst comprising transition metal imide of Group 6 substituted by alkyloxy, aryloxy, alkylamide and/or arylamide groups; high melting | ZEON CORPORATION (JP) | 2003-11-25 | — | — | US | disclosed |
| EP-1238996-A1 | NORBORNENE OPEN-RING POLYMERS, PRODUCTS OF HYDROGENATION THEREOF AND PROCESSES FOR THE PRODUCTION OF BOTH | Zeon Corporation (JP) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535638-B2 | Arylaminosilane compound, propylene polymerization catalyst and preparation thereof | RPS8, PARP8, PRMT8 | CYP1A2 1541/4885CYP2A6 2708/4885HTR1D 1371/4885 |
| US-20200369689-A1 | Arylaminosilane Compound, Propylene Polymerization Catalyst And Preparation Thereof | RPS8, PARP8, PRMT8 | CYP1A2 1541/4885CYP2A6 2708/4885HTR1D 1371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.