Doxenitoin

Doxenitoin

SCHEMBL667654

O=C1NCNC1(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
POLB P06746 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
CYP1A2 P05177 1/20 0.50
TSHR P16473 1/20 0.50
APEX1 P27695 1/20 0.50
CYP2C9 P11712 4/20 0.48
BLM P54132 2/20 0.48
PMP22 Q01453 2/20 0.48
CACNA1F O60840 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
HTR2A P28223 1/20 0.48
HRH1 P35367 1/20 0.48
SCN1A P35498 1/20 0.48
SCN4A P35499 1/20 0.48
CACNA1D Q01668 1/20 0.48
KCNH2 Q12809 1/20 0.48
CACNA1S Q13698 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Doxenitoin SCHEMBL27893787 0.98 KMT2A (0.49) KMT2APOLBTDP1MEN1CYP1A2
SCHEMBL11884797 0.82 CYP2C9 (0.47) KMT2APOLBTDP1MEN1CYP1A2
SCHEMBL18622047 0.71 MMP2 (0.64) KMT2APOLBTDP1MEN1CYP1A2
SCHEMBL20304019 0.69 TSHR (0.47) KMT2APOLBTDP1MEN1CYP1A2
Primidone SCHEMBL34221 0.67 KMT2A (1.00) KMT2APOLBTDP1MEN1CYP1A2
SCHEMBL20304196 0.67 TSHR (0.45) KMT2APOLBTDP1MEN1CYP1A2
SCHEMBL9666695 0.67 OPRM1 (0.40) KMT2APOLBTDP1MEN1CYP1A2
Phenytoin SCHEMBL3440 0.65 CYP2C9 (1.00) CYP2C9BLMPMP22CACNA1FALDH1A1
Phenytoin SCHEMBL5499612 0.65 CYP2C9 (1.00) CYP2C9BLMPMP22CACNA1FALDH1A1
SCHEMBL11147883 0.65 AKR1B1 (0.61) TDP1TSHRALDH1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 583 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464303-B2 Apparatus and method for providing individual sound zones Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-11-04 US claimed
CN-120065364-A Maneuvering GEO satellite searching method based on optical orbit measurement data 西北工业大学 2025-05-30 CN claimed
CN-119316860-B 5G perception Doppler diffusion clutter suppression method based on subcarrier domain and airspace combined dimensionality reduction processing 哈尔滨工业大学 2025-05-16 CN claimed
EP-4551520-A2 HIGH-ENERGY ALL-SOLID-STATE LITHIUM BATTERIES Yeda Research and Development Co. Ltd (IL) 2025-05-14 EP claimed
CN-119595909-A Method for detecting bacterial endotoxin of natural killer cell suspension 哈尔滨北科健康科技有限公司 2025-03-11 CN claimed
CN-119523452-A Heartbeat waveform reconstruction method based on MIMO millimeter wave radar signals 南京邮电大学 2025-02-28 CN claimed
CN-119316860-A 5G perception Doppler diffusion clutter suppression method based on subcarrier domain and airspace combined dimensionality reduction processing 哈尔滨工业大学 2025-01-14 CN claimed
CN-118784188-A Communication method and communication device 华为技术有限公司 2024-10-15 CN claimed
WO-2024208287-A1 COMMUNICATION METHOD AND COMMUNICATION APPARATUS 华为技术有限公司 2024-10-10 WO claimed
CN-118534252-A Power grid broadband oscillation positioning early warning system and method 中国南方电网有限责任公司 2024-08-23 CN claimed
EP-2026788-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2009-02-25 EP claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007141018-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2007-12-13 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20070043120-A1 Therapeutic combination for painful medical conditions UCB PHARMA GMBH (DE) 2007-02-22 US claimed
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy SRZ PROPERTIES, INC. (US) 2007-02-22 US claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy GRIN2B, GRIN2A, GRIN3A KMT2A 617/4885POLB 2633/4885TDP1 2854/4885
US-20070043120-A1 Therapeutic combination for painful medical conditions PDE1B, CA2, CACNA1S KMT2A 1606/4885POLB 4249/4885TDP1 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.