Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681075 | 0.89 | NQO2 (0.39) | IDO1HPGDALDH1A1KDM4EHTT | |
| SCHEMBL8771555 | 0.88 | IDO1 (0.39) | IDO1KDM4EHTTMAPTNQO2 | |
| SCHEMBL6676118 | 0.84 | CA2 (0.47) | KDM4EKMT2AMAPTGLALMNA | |
| SCHEMBL6675284 | 0.81 | ESRRG (0.42) | IDO1HPGDALDH1A1KDM4EHTT | |
| SCHEMBL6676958 | 0.79 | KDM4E (0.36) | KDM4EMAPTNQO2CA1CA2 | |
| SCHEMBL7241354 | 0.79 | IDO1 (0.46) | IDO1HPGDALDH1A1KDM4EHTT | |
| SCHEMBL6675306 | 0.78 | NQO2 (0.38) | KDM4EMAPTNQO2CA1CA2 | |
| SCHEMBL6678687 | 0.78 | KDM4E (0.38) | HPGDALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6674836 | 0.77 | KDM4E (0.34) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6676049 | 0.77 | IDO1 (0.55) | IDO1HPGDALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |