Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677739 | 0.85 | CA2 (0.45) | CA2CA1NAMPTPTGER4MAPT | |
| SCHEMBL6676265 | 0.85 | CA2 (0.40) | CA2CA1NAMPTPTGER4MAPT | |
| SCHEMBL6687614 | 0.84 | IDO1 (0.41) | CA2CA1MAPTKDM4ENPC1 | |
| SCHEMBL6681075 | 0.84 | NQO2 (0.39) | CA2CA1MAPTKDM4ENPC1 | |
| SCHEMBL6675284 | 0.84 | ESRRG (0.42) | CA2CA1NAMPTPTGER4MAPT | |
| SCHEMBL8771747 | 0.84 | CA2 (0.39) | CA2CA1NAMPTPTGER4MAPT | |
| SCHEMBL8771555 | 0.83 | IDO1 (0.39) | CA2CA1MAPTKDM4ENPC1 | |
| SCHEMBL6682001 | 0.83 | CA1 (0.41) | CA2CA1NAMPTMAPTKMT2A | |
| SCHEMBL6676958 | 0.78 | KDM4E (0.36) | CA2CA1MAPTKDM4ENPC1 | |
| SCHEMBL6679083 | 0.78 | HDAC1 (0.47) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |