Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677485 | 0.90 | ALDH1A1 (0.53) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6677031 | 0.86 | LMNA (0.59) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6682014 | 0.77 | ALDH1A1 (0.59) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6678678 | 0.75 | ADORA3 (0.60) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6678003 | 0.73 | KDM4E (0.55) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6678681 | 0.73 | ALDH1A1 (0.68) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL6678031 | 0.73 | LMNA (0.49) | MAPTKMT2AHPGDGAAKDM4E | |
| SCHEMBL2922655 | 0.73 | MMP13 (0.81) | KMT2AHPGDGAAALDH1A1NPC1 | |
| SCHEMBL6677039 | 0.72 | MEN1 (0.59) | MAPTKMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL4308980 | 0.71 | KMT2A (0.71) | KMT2AHPGDGAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |