SCHEMBL667836

SCHEMBL667836

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N(C)C)ncnc21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.63
▸ KMT2A Q03164 2/20 0.63
▸ ADORA3 P0DMS8 3/20 0.56
▸ ADORA1 P30542 2/20 0.55
▸ ADORA2A P29274 2/20 0.55
▸ ADORA2B P29275 2/20 0.55
▸ POLB P06746 1/20 0.54
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ SLC29A1 Q99808 2/20 0.54
▸ DPP4 P27487 1/20 0.54
▸ SLC28A1 O00337 1/20 0.54
▸ MAP3K7 O43318 1/20 0.54
▸ SLC28A2 O43868 1/20 0.54
▸ GAPDH P04406 1/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ STAT6 P42226 1/20 0.54
▸ PI4KA P42356 1/20 0.54
▸ PI4K2B Q8TCG2 1/20 0.54
▸ DOT1L Q8TEK3 1/20 0.54
▸ PI4K2A Q9BTU6 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14243961 1.00 MEN1 (0.63) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL19502714 1.00 MEN1 (0.63) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL29389308 1.00 MEN1 (0.63) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL3150637 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL20579764 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL29435131 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL1996593 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL18486352 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL157531 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A
SCHEMBL29390532 0.88 ADORA2A (0.69) MEN1KMT2AADORA3ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1329 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 — — US claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 — — WO claimed
US-20240363254-A1 METHOD FOR CHARACTERIZING A TUMOUR UNIVERSITÉ DE MONTPELLIER (FR) 2024-10-31 — — US claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 — — WO claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 — — EP claimed
EP-3460064-B1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) THE GENERAL HOSPITAL CORP D/B/A MASSACHUSETTS GENERAL HOSPITAL (US) 2024-02-07 — — EP claimed
WO-2023215498-A2 COMPOSITIONS AND METHODS FOR CD28 ANTAGONISM MODERNATX, INC. (US) 2023-11-09 — — WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 — — EP claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 — — WO claimed
US-20190175690-A1 COMPOSITIONS AND METHODS FOR CARDIAC REPAIR CHILDREN'S MEDICAL CENTER CORPORATION (US) 2019-06-13 — — US claimed
EP-3460064-A1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) The General Hospital Corporation d/b/a Massachusetts General Hospital (US) 2019-03-27 — — EP claimed
US-10086043-B2 Efficient protein expression in vivo using modified RNA (MOD-RNA) THE GENERAL HOSPITAL CORPORATION (US) 2018-10-02 — — US claimed
EP-2694660-B1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) MASSACHUSETTS GEN HOSPITAL (US) 2018-08-08 — — EP claimed
US-20140073687-A1 EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA) IMMUNE DISEASE INSTITUTE, INC. (US) 2014-03-13 — — US claimed
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2026-05-28 — — US disclosed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 — — EP disclosed
US-20120322864-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-12-20 — — US disclosed
US-20120046346-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-02-23 — — US disclosed
WO-2011130624-A2 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2011-10-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT MEN1 4242/4885KMT2A 2441/4885ADORA3 4335/4885
US-20190175690-A1 COMPOSITIONS AND METHODS FOR CARDIAC REPAIR YAP1, TNNI3, FABP3 MEN1 4403/4885KMT2A 1996/4885ADORA3 4202/4885
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS ELAVL1, IGF2BP2, FUS MEN1 3907/4885KMT2A 3684/4885ADORA3 2251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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