Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504772 | 0.78 | MAPT (0.36) | MAPTALDH1A1KDM4EHCAR3SMN1; SMN2 | |
| SCHEMBL2193445 | 0.75 | LMNA (0.33) | ALDH1A1HTTTSHRTDP1LMNA | |
| SCHEMBL455622 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL33832 | 0.72 | TDP1 (0.46) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL7136437 | 0.72 | TDP1 (0.46) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL6047841 | 0.72 | MAPT (0.41) | CA12CA1CA2CA4CA9 | |
| SCHEMBL58862 | 0.72 | MEN1 (0.36) | MAPTALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL2075135 | 0.71 | MAPT (0.36) | MAPTALDH1A1KDM4EHTTGAA | |
| SCHEMBL1179579 | 0.71 | PDE7A (0.35) | MAPTALDH1A1TSHRTDP1LMNA | |
| SCHEMBL3042315 | 0.71 | GPR35 (0.42) | ALDH1A1GAATSHRSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024558-A2 | LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-23 | — | — | WO | disclosed |
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |