Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.32 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | ADH1A | P07327 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490221 | 0.74 | GRIA1 (0.33) | — | |
| SCHEMBL209649 | 0.74 | — | — | |
| SCHEMBL605595 | 0.72 | — | — | |
| SCHEMBL5448562 | 0.70 | — | — | |
| SCHEMBL2006632 | 0.70 | GRIA1 (0.36) | — | |
| SCHEMBL605594 | 0.70 | — | — | |
| SCHEMBL26870066 | 0.70 | GRIA1 (0.31) | — | |
| SCHEMBL2504144 | 0.68 | ADH1B (0.30) | ADH1BADH1CADH1A | |
| SCHEMBL1446141 | 0.68 | GRIA1 (0.31) | — | |
| SCHEMBL2554677 | 0.67 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066977-B2 | Method of utilization of combination of benzophenone derivative or salt thereof and immunosuppressing agent, and pharmaceutical composition comprising these components | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-06-30 | — | — | US | disclosed |
| US-9012482-B2 | Drug containing benzophenone derivative or its salt | TOYAMA CHEMICAL CO., LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| EP-2258361-B1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNFalpha INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO LTD (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-2266557-B1 | COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | TOYAMA CHEMICAL CO LTD (JP) | 2013-08-14 | — | — | EP | disclosed |
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20120046326-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110039813-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-02-17 | — | — | US | disclosed |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2266557-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | Toyama Chemical Co., Ltd. (JP) | 2010-12-29 | — | — | EP | disclosed |
| EP-2258361-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | Toyama Chemical Co., Ltd. (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| WO-2008151735-A2 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | WO | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD (JP) | 2005-05-26 | — | — | US | disclosed |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SHUNICHI SHIOZAWA (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1481966-A1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039813-A1 | METHOD OF UTILIZATION OF COMBINATION OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND IMMUNOSUPPRESSING AGENT, AND PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPONENTS | SSB, NR3C2, BRPF3 | ADH1B 1611/4885ADH1C 1248/4885ADH1A 2460/4885 |
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | SLC7A1, NAT1, NACA | ADH1B 3818/4885ADH1C 1850/4885ADH1A 1592/4885 |
| US-20100240891-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | SOST, MYD88, TRAF6 | ADH1B 3006/4885ADH1C 3426/4885ADH1A 3131/4885 |
| US-20110020366-A1 | USE OF BENZOPHENONE DERIVATIVE OR SALT THEREOF AND TNF ALPHA INHIBITOR IN COMBINATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE OR SALT THEREOF AND THE INHIBITOR | TNF, NFKBIA, CHUK | ADH1B 2379/4885ADH1C 1283/4885ADH1A 2504/4885 |
| US-20050113400-A1 | Inhibitors of transcription factor AP-1; autoimmune diseases; rheumatoid arthritis; high safety and excellent pharmacokinetics in vivo | SP1, AP1G1, JUN | ADH1B 3021/4885ADH1C 2423/4885ADH1A 1532/4885 |
| US-20120046326-A1 | DRUG CONTAINING BENZOPHENONE DERIVATIVE OR ITS SALT | SOST, MYD88, TRAF6 | ADH1B 3006/4885ADH1C 3426/4885ADH1A 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.